.gmeta[data-astro-cid-oianxrz4]{display:flex;flex-wrap:wrap;justify-content:center;gap:8px 20px;margin-top:24px;font-size:13px;color:var(--muted)}.gmeta[data-astro-cid-oianxrz4] span[data-astro-cid-oianxrz4]{display:inline-flex;align-items:center;gap:6px}.gmeta[data-astro-cid-oianxrz4] svg{color:var(--emerald)}.chip[data-astro-cid-oianxrz4]{display:inline-block;font:600 10px IBM Plex Mono,monospace;letter-spacing:.08em;text-transform:uppercase;padding:3px 9px;border-radius:999px;white-space:nowrap;margin-right:6px}.chip--reg[data-astro-cid-oianxrz4]{background:#eceff7;color:#3d4a6b}.chip--human[data-astro-cid-oianxrz4]{background:#d4f5e9;color:#0a6644}.chip--animal[data-astro-cid-oianxrz4]{background:#fdf0de;color:#8a5514}.glance[data-astro-cid-oianxrz4]{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1.2fr);gap:24px;align-items:start}.count[data-astro-cid-oianxrz4]{background:#fff;border:1px solid var(--line);border-radius:16px;padding:22px 24px}.count__k[data-astro-cid-oianxrz4]{font:500 11px IBM Plex Mono,monospace;letter-spacing:.1em;text-transform:uppercase;color:var(--emerald);margin:0 0 10px}.count__big[data-astro-cid-oianxrz4]{font-family:Fraunces,serif;font-size:clamp(26px,3.4vw,34px);color:var(--ink);margin:0 0 12px;line-height:1.15}.count__big[data-astro-cid-oianxrz4] strong[data-astro-cid-oianxrz4]{font-size:1.5em;color:var(--green)}.count__line[data-astro-cid-oianxrz4]{font-size:16px;color:var(--ink);margin:0;padding:10px 0;border-top:1px solid var(--line);line-height:1.45}.count__line[data-astro-cid-oianxrz4] strong[data-astro-cid-oianxrz4]{font-family:IBM Plex Mono,monospace;color:var(--green)}.count__note[data-astro-cid-oianxrz4]{font-size:13px;color:var(--muted);margin:12px 0 0;line-height:1.55}.glance__list[data-astro-cid-oianxrz4]{margin:0;background:#fff;border:1px solid var(--line);border-radius:16px;padding:8px 20px}.glance__list[data-astro-cid-oianxrz4] div[data-astro-cid-oianxrz4]{display:grid;grid-template-columns:130px minmax(0,1fr);gap:12px;padding:12px 0;border-bottom:1px solid var(--line)}.glance__list[data-astro-cid-oianxrz4] div[data-astro-cid-oianxrz4]:last-child{border-bottom:0}.glance__list[data-astro-cid-oianxrz4] dt[data-astro-cid-oianxrz4]{font:500 11px IBM Plex Mono,monospace;letter-spacing:.1em;text-transform:uppercase;color:var(--emerald);padding-top:3px}.glance__list[data-astro-cid-oianxrz4] dd[data-astro-cid-oianxrz4]{margin:0;font-size:15px;color:var(--ink);line-height:1.5}.ht-wrap[data-astro-cid-oianxrz4]{border:1px solid var(--line);border-radius:14px;overflow-x:auto;-webkit-overflow-scrolling:touch;background:#fff}.ht[data-astro-cid-oianxrz4]{width:100%;min-width:880px;border-collapse:collapse;font-size:14px}.ht__cap[data-astro-cid-oianxrz4]{caption-side:top;text-align:left;padding:12px 16px 0;font:500 10px IBM Plex Mono,monospace;letter-spacing:.12em;text-transform:uppercase;color:#9aa8a2}.ht[data-astro-cid-oianxrz4] thead[data-astro-cid-oianxrz4] th[data-astro-cid-oianxrz4]{font:500 10px IBM Plex Mono,monospace;letter-spacing:.12em;text-transform:uppercase;color:#9aa8a2;text-align:left;padding:12px 16px;border-bottom:1px solid var(--line);background:#f8fbf9;white-space:nowrap}.ht[data-astro-cid-oianxrz4] tbody[data-astro-cid-oianxrz4] th[data-astro-cid-oianxrz4],.ht[data-astro-cid-oianxrz4] td[data-astro-cid-oianxrz4]{padding:14px 16px;border-bottom:1px solid var(--line);vertical-align:top;line-height:1.5;text-align:left}.ht[data-astro-cid-oianxrz4] tbody[data-astro-cid-oianxrz4] th[data-astro-cid-oianxrz4]{width:96px}.ht[data-astro-cid-oianxrz4] thead[data-astro-cid-oianxrz4] th[data-astro-cid-oianxrz4]:nth-child(2){width:34%}.ht[data-astro-cid-oianxrz4] thead[data-astro-cid-oianxrz4] th[data-astro-cid-oianxrz4]:nth-child(3){width:22%}.ht[data-astro-cid-oianxrz4] td[data-astro-cid-oianxrz4]{color:var(--muted)}.ht[data-astro-cid-oianxrz4] tbody[data-astro-cid-oianxrz4] tr[data-astro-cid-oianxrz4]:last-child th[data-astro-cid-oianxrz4],.ht[data-astro-cid-oianxrz4] tbody[data-astro-cid-oianxrz4] tr[data-astro-cid-oianxrz4]:last-child td[data-astro-cid-oianxrz4]{border-bottom:0}.ht[data-astro-cid-oianxrz4] tbody[data-astro-cid-oianxrz4] tr[data-astro-cid-oianxrz4]:target{background:#fdf6ec}.ht__year[data-astro-cid-oianxrz4]{display:block;font:600 13px IBM Plex Mono,monospace;color:var(--ink)}.ht__title[data-astro-cid-oianxrz4]{display:block;color:var(--ink);font-size:15px;margin-bottom:6px;line-height:1.4}.ht__chip[data-astro-cid-oianxrz4]{display:inline-block;font:600 10px IBM Plex Mono,monospace;letter-spacing:.05em;text-transform:uppercase;padding:2px 8px;border-radius:999px;margin-bottom:6px}.ht__chip--placebo[data-astro-cid-oianxrz4]{background:#d4f5e9;color:#0a6644}.ht__chip--uncontrolled[data-astro-cid-oianxrz4]{background:#fde4d0;color:#8a3412}.ht__meta[data-astro-cid-oianxrz4]{display:block;font-size:13px;line-height:1.55;margin-top:4px}.ht__n[data-astro-cid-oianxrz4]{display:block;font:600 20px IBM Plex Mono,monospace;color:var(--ink)}.ht__res[data-astro-cid-oianxrz4]{display:block;color:var(--ink);font-size:14px;line-height:1.55}.ht--counts[data-astro-cid-oianxrz4]{min-width:760px}.ht--counts[data-astro-cid-oianxrz4] tbody[data-astro-cid-oianxrz4] th[data-astro-cid-oianxrz4]{width:30%}.ht__src[data-astro-cid-oianxrz4]{display:block;color:var(--ink);font-weight:600;font-size:14px;line-height:1.4}.ht__cnt[data-astro-cid-oianxrz4]{color:var(--ink)}.ht__link[data-astro-cid-oianxrz4]{display:flex;align-items:center;min-height:44px;color:var(--green);font-weight:600;font-size:13px;text-decoration:underline;text-underline-offset:2px}.note[data-astro-cid-oianxrz4]{font-size:14px;color:var(--muted);line-height:1.65;margin:20px 0 0;max-width:760px;padding-left:14px;border-left:3px solid var(--amber);overflow-wrap:anywhere}.note[data-astro-cid-oianxrz4] a[data-astro-cid-oianxrz4]{color:var(--green);text-decoration:underline;text-underline-offset:2px}.note[data-astro-cid-oianxrz4] code[data-astro-cid-oianxrz4]{font-size:12px;background:#f1f5f3;padding:1px 4px;border-radius:4px}.cite[data-astro-cid-oianxrz4]{margin-top:28px;display:grid;grid-template-columns:minmax(0,1fr) auto;gap:20px 28px;align-items:center;background:#f8fbf9;border:1px solid var(--line);border-radius:16px;padding:22px 24px}.cite__title[data-astro-cid-oianxrz4]{font-family:Fraunces,serif;font-size:clamp(19px,2.4vw,22px);color:var(--ink);margin:0 0 6px}.cite__lead[data-astro-cid-oianxrz4]{font-size:14px;color:var(--muted);line-height:1.6;margin:0 0 12px}.cite__ref[data-astro-cid-oianxrz4]{font:400 13px/1.6 IBM Plex Mono,monospace;color:var(--ink);background:#fff;border:1px solid var(--line);border-radius:10px;padding:12px 14px;margin:0;overflow-wrap:anywhere;user-select:all}.cite__actions[data-astro-cid-oianxrz4]{display:flex;flex-direction:column;gap:10px;min-width:220px}.cite__btn[data-astro-cid-oianxrz4]{display:inline-flex;align-items:center;justify-content:center;min-height:44px;padding:0 18px;border-radius:999px;background:var(--green);color:#fff;font-size:14px;font-weight:600;border:1px solid var(--green);cursor:pointer;text-decoration:none}.cite__btn--ghost[data-astro-cid-oianxrz4]{background:#fff;color:var(--green)}.cite__lead--embed[data-astro-cid-oianxrz4]{margin:16px 0 8px}.cite__lead--embed[data-astro-cid-oianxrz4] a[data-astro-cid-oianxrz4]{color:var(--green);font-weight:600}.cite__code[data-astro-cid-oianxrz4]{white-space:pre-wrap;font-size:12px;max-height:180px;overflow:auto}.sz[data-astro-cid-oianxrz4]{margin:0;max-width:900px;background:#fff;border:1px solid var(--line);border-radius:16px;padding:22px 24px}.sz__cap[data-astro-cid-oianxrz4]{font-family:Fraunces,serif;font-size:clamp(18px,2.2vw,21px);color:var(--ink);margin-bottom:6px}.sz__group[data-astro-cid-oianxrz4]{font:500 11px IBM Plex Mono,monospace;letter-spacing:.1em;text-transform:uppercase;color:var(--emerald);margin:16px 0 8px}.sz__list[data-astro-cid-oianxrz4]{list-style:none;padding:0;margin:0;display:flex;flex-direction:column;gap:8px}.sz__row[data-astro-cid-oianxrz4]{display:grid;grid-template-columns:minmax(0,300px) minmax(0,1fr) 40px;gap:12px;align-items:center}.sz__name[data-astro-cid-oianxrz4]{color:var(--ink);font-size:14px;text-decoration:underline;text-underline-offset:2px;min-height:32px;display:flex;align-items:center;line-height:1.3}.sz__track[data-astro-cid-oianxrz4]{height:14px;background:#eef4f1;border-radius:999px;overflow:hidden}.sz__bar[data-astro-cid-oianxrz4]{display:block;height:100%;border-radius:999px}.sz__bar--placebo[data-astro-cid-oianxrz4],.sz__dot--placebo[data-astro-cid-oianxrz4]{background:#0d6b4f}.sz__bar--uncontrolled[data-astro-cid-oianxrz4],.sz__dot--uncontrolled[data-astro-cid-oianxrz4]{background:#e08a4f}.sz__bar--trial[data-astro-cid-oianxrz4],.sz__dot--trial[data-astro-cid-oianxrz4]{background:#9fb8ae}.sz__n[data-astro-cid-oianxrz4]{font:600 14px IBM Plex Mono,monospace;color:var(--ink);text-align:right}.sz__key[data-astro-cid-oianxrz4]{display:flex;flex-wrap:wrap;align-items:center;gap:6px 10px;font-size:13px;color:var(--muted);margin:18px 0 0}.sz__item[data-astro-cid-oianxrz4]{display:inline-flex;align-items:center;gap:6px}.sz__dot[data-astro-cid-oianxrz4]{display:inline-block;width:12px;height:12px;border-radius:3px}.sz__note[data-astro-cid-oianxrz4]{font-size:13px;color:var(--muted);margin:10px 0 0;line-height:1.5}.cards[data-astro-cid-oianxrz4]{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:14px}.card[data-astro-cid-oianxrz4]{background:#fff;border:1px solid var(--line);border-radius:14px;padding:18px 20px;display:flex;flex-direction:column;gap:6px}.card[data-astro-cid-oianxrz4]:target{background:#fdf6ec}.card__top[data-astro-cid-oianxrz4]{display:flex;flex-wrap:wrap;gap:8px;align-items:center}.card__status[data-astro-cid-oianxrz4]{font:600 10px IBM Plex Mono,monospace;letter-spacing:.06em;text-transform:uppercase;padding:3px 9px;border-radius:999px;background:#eceff7;color:#3d4a6b}.card__status--recruiting[data-astro-cid-oianxrz4]{background:#d4f5e9;color:#0a6644}.card__status--completed[data-astro-cid-oianxrz4]{background:#fdf0de;color:#8a5514}.card__phase[data-astro-cid-oianxrz4]{font:500 11px IBM Plex Mono,monospace;color:#6b7b74}.card__title[data-astro-cid-oianxrz4]{font-size:16px;color:var(--ink);line-height:1.35}.card[data-astro-cid-oianxrz4] p[data-astro-cid-oianxrz4]{font-size:14px;color:var(--muted);line-height:1.6;margin:0}.card__link[data-astro-cid-oianxrz4]{color:var(--green);font-weight:600;font-size:14px;text-decoration:underline;text-underline-offset:2px;display:inline-flex;align-items:center;min-height:44px}.split[data-astro-cid-oianxrz4]{display:grid;grid-template-columns:minmax(0,1.6fr) minmax(0,1fr);gap:32px;align-items:start}.split__main[data-astro-cid-oianxrz4] p[data-astro-cid-oianxrz4]{font-size:16px;color:var(--muted);line-height:1.75;margin:0 0 16px}.split__main[data-astro-cid-oianxrz4] a[data-astro-cid-oianxrz4]{color:var(--green);text-decoration:underline;text-underline-offset:2px}.split__main[data-astro-cid-oianxrz4] .lead2[data-astro-cid-oianxrz4]{font-size:clamp(17px,2vw,19px);color:var(--ink);line-height:1.6}.split__side[data-astro-cid-oianxrz4]{background:#fff;border:1px solid var(--line);border-left:4px solid var(--emerald);border-radius:14px;padding:20px}.split__k[data-astro-cid-oianxrz4]{display:block;font:500 10px IBM Plex Mono,monospace;letter-spacing:.14em;text-transform:uppercase;color:var(--emerald);margin-bottom:8px}.split__side[data-astro-cid-oianxrz4] p[data-astro-cid-oianxrz4]{font-size:15px;color:var(--ink);line-height:1.6;margin:0 0 12px}.split__side[data-astro-cid-oianxrz4] a[data-astro-cid-oianxrz4]{color:var(--green);font-weight:600;text-decoration:underline;text-underline-offset:2px;display:inline-flex;align-items:center;min-height:44px}.case[data-astro-cid-oianxrz4]{max-width:860px;background:#fff;border:1px solid var(--line);border-radius:16px;padding:24px;box-shadow:0 10px 30px -22px #0d262059}.case__head[data-astro-cid-oianxrz4]{display:flex;flex-direction:column;align-items:flex-start;gap:10px;margin-bottom:12px}.case__head[data-astro-cid-oianxrz4] strong[data-astro-cid-oianxrz4]{font-family:Fraunces,serif;font-size:clamp(19px,2.4vw,22px);color:var(--ink);line-height:1.3}.case[data-astro-cid-oianxrz4] p[data-astro-cid-oianxrz4]{font-size:15px;color:var(--muted);line-height:1.75;margin:0 0 10px}.case[data-astro-cid-oianxrz4] a[data-astro-cid-oianxrz4]{color:var(--green);text-decoration:underline;text-underline-offset:2px}.gaps[data-astro-cid-oianxrz4]{margin:0;padding:0 0 0 20px;max-width:860px;display:flex;flex-direction:column;gap:12px}.gaps[data-astro-cid-oianxrz4] li[data-astro-cid-oianxrz4]{font-size:15px;color:var(--muted);line-height:1.65}.gaps[data-astro-cid-oianxrz4] strong[data-astro-cid-oianxrz4]{color:var(--ink)}.how[data-astro-cid-oianxrz4]{list-style:none;padding:0;margin:0;max-width:860px}.how__step[data-astro-cid-oianxrz4]{display:flex;gap:16px;align-items:flex-start;padding:16px 0;border-bottom:1px solid var(--line)}.how__step[data-astro-cid-oianxrz4]:last-child{border-bottom:0}.how__n[data-astro-cid-oianxrz4]{width:32px;height:32px;border-radius:999px;background:var(--green);color:#fff;font:600 14px IBM Plex Mono,monospace;display:flex;align-items:center;justify-content:center;flex-shrink:0}.how__step[data-astro-cid-oianxrz4] strong[data-astro-cid-oianxrz4]{font-size:16px;color:var(--ink)}.how__step[data-astro-cid-oianxrz4] p[data-astro-cid-oianxrz4]{font-size:15px;color:var(--muted);line-height:1.6;margin:4px 0 0}.log[data-astro-cid-oianxrz4]{list-style:none;padding:0;margin:24px 0 0;max-width:860px}.log[data-astro-cid-oianxrz4] li[data-astro-cid-oianxrz4]{border-top:1px solid var(--line);padding:14px 0 0;display:flex;flex-direction:column;gap:4px}.log__date[data-astro-cid-oianxrz4]{font:600 12px IBM Plex Mono,monospace;color:var(--emerald)}.log[data-astro-cid-oianxrz4] p[data-astro-cid-oianxrz4]{font-size:14px;color:var(--muted);line-height:1.6;margin:0}.cap[data-astro-cid-oianxrz4]{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,460px);gap:40px;align-items:center}.cap__title[data-astro-cid-oianxrz4]{color:#fff;font-size:clamp(26px,3.4vw,36px);line-height:1.12;margin:0 0 12px}.cap__lead[data-astro-cid-oianxrz4]{color:#bfe3d8;font-size:16px;line-height:1.65;margin:0;max-width:560px}.cap__form[data-astro-cid-oianxrz4] form{flex-wrap:wrap;max-width:none!important}.cap__form[data-astro-cid-oianxrz4] input{min-width:0;min-height:48px}.cap__form[data-astro-cid-oianxrz4] button{min-height:48px}.cap__form[data-astro-cid-oianxrz4] p{color:#7fe0c2!important}.page-footer[data-astro-cid-oianxrz4]{margin-top:32px;display:flex;flex-direction:column;gap:20px}@media(max-width:900px){.glance[data-astro-cid-oianxrz4],.split[data-astro-cid-oianxrz4],.cap[data-astro-cid-oianxrz4]{grid-template-columns:1fr;gap:24px}}@media(max-width:640px){.glance__list[data-astro-cid-oianxrz4] div[data-astro-cid-oianxrz4]{grid-template-columns:1fr;gap:4px}.cards[data-astro-cid-oianxrz4]{grid-template-columns:1fr}.count[data-astro-cid-oianxrz4],.sz[data-astro-cid-oianxrz4]{padding:18px}.sz__row[data-astro-cid-oianxrz4]{grid-template-columns:minmax(0,1fr) 40px;gap:4px 10px}.sz__name[data-astro-cid-oianxrz4]{grid-column:1 / -1;min-height:0}.sz__key[data-astro-cid-oianxrz4]{flex-direction:column;align-items:flex-start}.ht-wrap[data-astro-cid-oianxrz4]{overflow:visible;border:0;background:transparent}.ht[data-astro-cid-oianxrz4]{min-width:0;display:block}.ht[data-astro-cid-oianxrz4] thead[data-astro-cid-oianxrz4]{display:none}.ht[data-astro-cid-oianxrz4] tbody[data-astro-cid-oianxrz4],.ht[data-astro-cid-oianxrz4] tr[data-astro-cid-oianxrz4]{display:block}.ht[data-astro-cid-oianxrz4] tr[data-astro-cid-oianxrz4]{background:#fff;border:1px solid var(--line);border-radius:14px;padding:8px 0;margin-top:12px}.ht[data-astro-cid-oianxrz4] tbody[data-astro-cid-oianxrz4] th[data-astro-cid-oianxrz4],.ht[data-astro-cid-oianxrz4] td[data-astro-cid-oianxrz4]{display:block;border-bottom:0;padding:6px 16px;width:auto}.ht[data-astro-cid-oianxrz4] td[data-astro-cid-oianxrz4][data-label]:before{content:attr(data-label);display:block;font:500 10px IBM Plex Mono,monospace;letter-spacing:.12em;text-transform:uppercase;color:#9aa8a2;margin-bottom:2px}.ht__cap[data-astro-cid-oianxrz4]{display:block;padding:0}.cite[data-astro-cid-oianxrz4]{grid-template-columns:1fr;padding:18px}.cite__actions[data-astro-cid-oianxrz4]{min-width:0}.kit-section__title{font-size:clamp(28px,7vw,38px)}}