Curcumin

Herb studied for inflammation support, joint comfort, recovery. How it works, the dose and timing studied, what it interacts with, and the research behind the grade.

Grade B evidence moderate: promising but smaller or mixed human trials Also known as Turmeric extract
All compounds
Best for Inflammation support, Joint comfort, Recovery
Typical dose 500–1,000 mg of a bioavailability-enhanced extract
Timing With a fat-containing meal; formulations with piperine aid absorption
Category Herb
The daily email

Peptide news each morning, with the study linked

New trials, FDA changes and side-effect reports, written in plain English. Every result says whether it was tested in people or in animals.

Free. One email a morning. Unsubscribe in one click.

What it is and the mechanism

Polyphenol from turmeric that modulates inflammatory signaling pathways including NF-kB and COX-2, and has antioxidant activity. Poor on its own absorption is improved by piperine or lipid and phytosome formulations.

When and how much to take

The dose below reflects the range used in published research. Match the form alongside the milligrams. Set your own wake and bed times to map the timing onto your day.

When to take Curcumin

Dose: 500–1,000 mg of a bioavailability-enhanced extract. Set your own wake and bed times to map the guidance onto your day.

12a6a12p6pDAY1 dose
12 pmAnytime. Timing is flexible. Pick a slot you can keep consistent.

These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Interactions and cautions

Read these before combining this with other supplements or medication. The risk is rarely the headline, it is the interaction you did not check.

Interactions
  • Anticoagulants, possible additive blood-thinning effect
  • CYP and P-gp substrates, piperine-enhanced products can alter drug levels
Cautions
  • GI upset at higher doses
  • Gallstones or bile duct obstruction, avoid
  • Stop before surgery due to bleeding risk

What pairs well, and what to keep apart

Derived from shared topics, complementary categories, and the interaction list. Introduce one compound at a time so you can tell what works.

Keep apart from

No direct compound conflicts derived. Still check the interactions list above against your medication.

Compounds in the same topics

Often considered alongside this one. Each carries its own evidence grade.

More compounds for longevity & aging

Other compounds studied for longevity & aging, strongest human evidence first.